ECDC pilot study uncovers the burden of infectious diseases in Europe

The pilot study was designed to test the potential use of the disease burden concept in the field of infectious diseases, including data quality and availability.

The disease burden of seven infectious diseases (influenza, measles, HIV, campylobacteriosis, infection with enterohaemorrhagic Escherichia coli, salmonellosis and tuberculosis) in Europe was estimated by calculating Disability Adjusted Life Years (DALYs), a composite measure that attempts to combine mortality, incidence and sequelae, taking duration and severity into account.

The results show that the relative burden of diseases as measured by DALYs differs from that only measured by incidence or mortality. Several limitations regarding data availability and quality have been identified, resulting in an underestimation of the true burden of disease in this pilot.

Notwithstanding these, HIV-infection, tuberculosis (TB) and influenza are estimated to cause the highest burden in Europe among the selected diseases. The burden of foodborne diseases (campylobacteriosis, infection with enterohaemorrhagic Escherichia coli and salmonellosis) and in particular of measles is lower.

A consideration of the relative comparison of burden between diseases can be useful when tackling the difficult, sensitive but necessary task of identifying priority actions. A low disease burden needs continual prevention and control whereas a high burden indicates the need for additional interventions. The evidence base provided by the analysis of data using DALYs would lead to priority actions to tackle HIV/AIDS, tuberculosis and influenza.

Data are available in the EuroSurveillance’s website

For further information

 ECDC website
 Pilot Study
 DALYs indicators

EPHA related articles

 Joining forces to combat Tuberculosis in Europe
 Open Forum on Key Issues in Tuberculosis Drug Development
 Conference on "Tuberculosis - The Way Forward", London - 16 October 2006
 Commission adopts new Communication to confront HIV/AIDS, Malaria and Tuberculosis outside the EU
 Cooperation and Immunisation needed to Control Infectious Diseases
 article 1817